Acute Motor Axonal Neuropathy with Bulbar Symptoms- Case report

Abstract

Acute motor axonal neuropathy (AMAN), a rare variant of Guillain-Barré Syndrome (GBS) presents with rapid paralysis. A 14-year-old boy exhibited bulbar symptoms alongside limb weakness. Clinical examination revealed positive Gowers’s sign and inability to walk on toes. Sensory function was normal, with intact reflexes and sphincter control. Investigations including cerebrospinal fluid, viral serology, and magnetic resonance imaging of the brain and spinal cord yielded no abnormalities. Electromyography confirmed motor axonal polyneuropathy. Treatment with intravenous immunoglobulin led to symptom regression within two weeks. AMAN, lacking sensory involvement, often follows a severe course, necessitating consideration of IVIg due to hyperreactive humoral response.